|Brand Name:||DM Pharma|
|Composition:||Aceclofenac 100mg + Thiocolchicoside 4mg|
Aceclofenac and Thiocolchicoside Tablets for Pain and Inflammation
Aceclofenac – Aceclofenac a nonsteroidal anti-inflammatory drug (NSAID) is used to relief pain and inflammation in rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Aceclofenac should not be given to people with porphyria or breast-feeding mothers and is not recommended for children. It should be avoided near term in a pregnant woman because of the risk of having a patent ductus arteriosus in the neonate.
Thiocolchicoside – Thiocolchicoside is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine receptor antagonist with similar potency and nicotinic acetylcholine receptors to a much lesser extent. It has a powerful convulsant activity and should not be used in seizure-prone individuals.
MECHANISM OF ACTION: Acclor-T tablet, a combination of aceclofenac and thiocolchicoside is an anti-inflammatory painkiller. Aceclofenac works by blocking the effect of natural substances called cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the body, called prostaglandins. Some prostaglandins are produced at sites of injury or damage and cause pain and inflammation. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased. Thiocolchicoside is a muscle relaxing agent that works through selective binding to the GABA-A receptor. It prevents muscle contractions by activating the GABA inhibitory motor pathway.
SIDE EFFECTS: Some of the common side effects caused by aceclofenac and thiocolchicoside are:
As directed by the physician.
Store in a cool, dry and dark place.
Note – The Database is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. Consult with your medical practitioner before taking any medication.