|Brand Name:||DM Pharma|
|Composition:||Diacerein 50mg + Glucosamine Sulphate 750mg + Methylsulfonylmethane 250mg|
DICRIN-GM Diacerein with Glucosamine for Osteoarthritis
Diacerein – Diacerein, also known as diacetylrhein, is a medicine that belongs to the anthraquinone class and is used to treat degenerative diseases of the bones and joints. It is used to relieve pain and swelling associated with Osteoarthritis. This medicine is slow acting and is used as a long-term treatment option for osteoarthritis. Diacerein is a symptomatic slow-acting drug in osteoarthritis (SYSADOA) with anti-inflammatory, anti-catabolic and pro-anabolic properties on cartilage and synovial membrane.
Diacerein works by blocking the actions of interleukin-1 beta, a protein involved in the inflammation and destruction of cartilage that plays a role in the development of symptoms of degenerative joint diseases such as osteoarthritis. Due to its specific mode of action, which does not involve the inhibition of prostaglandin synthesis, diacerein has been shown to have anti-osteoarthritis and cartilage stimulating properties in vitro and animal models.
Glucosamine Sulphate – Glucosamine is a natural compound found in cartilage — the tough tissue that cushions joints. Glucosamine is a naturally occurring chemical found in the human body. It helps our body to rebuild cartilage and replenish fluid around the joints (synovial fluid). It also helps prevent the breakdown of cartilage.
Glucosamine is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies. It is an amino sugar and precursor of glycosylated proteins and lipids. Since glucosamine is a precursor for glycosaminoglycans, and glycosaminoglycans are a major component of joint cartilage, supplemental glucosamine may help to rebuild cartilage and treat arthritis.
Methylsulfonylmethane – Methylsulfonylmethane or MSM is a naturally occurring chemical supplement used in the treatment of various conditions such as osteoarthritis, tendinitis, musculoskeletal pain, etc. It is generally used in combination with other medicines for a more effective treatment.
Mechanism of Action: Dicrin-GM tablets, a combination of Diacerein, Glucosamine, and MSM is medicine for Osteoarthritis. Diacerein works by blocking the actions of interleukin-1 beta, a protein involved in the inflammation and destruction of cartilage. Glucosamine helps in rebuilding the cartilage and replenish fluid around the joints. MSM with anti-inflammatory properties improved symptoms of pain and physical function.
INDICATION: Dicrin-GM tablets found its uses in the following
SIDE EFFECTS: Some of the common side effects found for Diacerein, Glucosamine and MSM are
As directed by the physician.
Store in a cool, dry and dark place. Protect from direct sunlight, heat, and moisture.
Note – The Database is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. Consult with your medical practitioner before taking any medication.